2017

■"The Generation of Human γδT Cell-Derived Induced Pluripotent Stem Cells from Whole Peripheral Blood Mononuclear Cell Culture."
Daisuke Watanabe, Michiyo Koyanagi-Aoi, Mariko Taniguchi-Ikeda, Yukiko Yoshida , Takeshi Azuma, Takashi Aoi
Stem Cells Transl Med, 2017 Nov 21

■"The Tissue-Reconstructing Ability of Colon CSCs Is Enhanced by FK506 and Suppressed by GSK3 Inhibition."
Ryo Ishida, Michiyo Koyanagi-Aoi, Nobu Oshima, Yoshihiro Kakeji, Takashi Aoi
Mol Cancer Res, 2017 Oct;15(10):1455-1466.

■"Interleukin-6 blockade attenuates lung cancer tissue construction integrated by cancer stem cells"
Hiroyuki Ogawa, Michiyo Koyanagi-Aoi, Kyoko Otani, Yoh Zen, Yoshimasa Maniwa, Takashi Aoi
Sci Rep,7, 2017 Sep 26;7(1):12317

2016

■”Current issues on cancer stem cell researches”
Ishida R, Kakeji Y, Aoi T
Cytometry Research Vol.26(2), 2016 Pages 7-13

■”Epigenetic Variation between Human Induced Pluripotent Stem Cell Lines Is an Indicator of Differentiation Capacity”
Nishizawa M, Chonabayashi K, Nomura M, Tanaka A, Nakamura M, Inagaki A, Nishikawa M, Takei I, Oishi A, Tanabe K, Ohnuki M,
Yokota H, Koyanagi-Aoi M, Okita K, Watanabe A, Takaori-Kondo A, Yamanaka S, Yoshida Y
Cell Stem Cell,19,1-14,2016

■”10th anniversary of iPS Cells: The challenges that lie ahead”
Aoi T
The Journal of Biochemistry,160(3), 2016 Pages121-9

■”Biology of Lung Cancer - Genetic Mutation, Epithelial-Mesenchymal Transition and Cancer Stem Cells”
Aoi T
General Thoracic and Cardiovascular Surgery,64(9), 2016 Pages517-23

2015

■”Impact of National and International Stem Cell Banking Initiatives on progress in the field of cell therapy:IABS-JST Joint Workshop:Summary for Session 5.”
Aoi T, Stacey G
Biologicals, vol.43,Issue 5, 2015 Pages399-401

■”Report of the international conference on regulatory endeavors towards the sound development of human cell therapy products.”
Hayakawa T, Aoi T, Bravery C, Hoogendoorn K, Knezevic I, Koga J, Maeda D, Matsuyama A, McBlane J, Morio T, Petricciani J, Rao M, Ridgway A, Sato D, Sato Y, Stacey G, Sakamoto N, Trouvin J.H, Umezawa A, Yamato M, Yano K, Yokote H, Yoshimatsu K, Zorzi-Morre P
Biologicals, vol.43,Issue 5, 2015 Pages283-297

■”A study on ensuring the quality and safety of pharmaceuticals and medical devices derived from the processing of autologous human somatic stem cells.”
Hayakawa T, Aoi T, Umezawa A, Ozawa K, Sato Y, Sawa Y, Matsuyama A, Yamanaka S, Yamato M
Regenerative Therapy, vol.2, 2015 Pages57-69

■”A study on ensuring the quality and safety of pharmaceuticals and medical devices derived from the processing of allogenic human somatic stem cells.”
Hayakawa T, Aoi T, Umezawa A, Ozawa K, Sato Y, Sawa Y, Matsuyama A, Yamanaka S, Yamato M
Regenerative Therapy, vol.2, 2015 Pages70-80

■”A study on ensuring the quality and safety of pharmaceuticals and medical devices derived from processing of autologous human induced pluripotent stem (-like) cells.”
Hayakawa T, Aoi T, Umezawa A, Ozawa K, Sato Y, Sawa Y, Matsuyama A, Yamanaka S, Yamato M
Regenerative Therapy, vol.2, 2015 Pages81-94

■”A study on ensuring the quality and safety of pharmaceuticals and medical devices derived from processing of allogenic human induced pluripotent stem (-like) cells.”
Hayakawa T, Aoi T, Umezawa A, Ozawa K, Sato Y, Sawa Y, Matsuyama A, Yamanaka S, Yamato M
Regenerative Therapy, vol.2, 2015 Pages95-108

■”A study on ensuring the quality and safety of pharmaceuticals and medical devices derived from the processing of human embryonic stem cells.”
Hayakawa T, Aoi T, Umezawa A, Ozawa K, Sato Y, Sawa Y, Matsuyama A, Yamanaka S, Yamato M
Regenerative Therapy, vol.2, 2015 Pages109-122

■「Gene Therapy and Cell Therapy Through the Liver -Current Aspects and Future Prospects」
Chapter 10 "The Way to Clinical Applications of Human Pluripotent Stem Cells"
Springer 2015, PartⅢ, Pages 95-103

2014

■”Induction of cancer stem cell properties in colon cancer cells by defined factors.”
Oshima N, Yamada Y, Nagayama S, Kawada K, Hasegawa S, Okabe H, Sakai Y, Aoi T
PLoS One 9: e101735. (2014)

2013

■”Gamma-delta T Cells may Function as Carrier Vehicles in Adenovirus Vector-based Gene Therapy”
Naoe M, Ogawa Y, Hasebe Y, Fuji K, Iwamoto S, Mizuguchi H, Aoi T, Terao S.
J Cancer Sci Ther Vol.5(11), 2013 Pages 384-390

■”Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness.”
Kondo T, Asai M, Tsukita K, Kutoku Y, Ohsawa Y, Sunada Y, Imamura K, Egawa N, Yahata N, Okita K, Takahashi K, Asaka I, Aoi T, Watanabe A, Watanabe K, Kadoya C, Nakano R, Watanabe D, Maruyama K, Hori O, Hibino S, Choshi T, Nakahata T, Hioki H, Kaneko T, Naitoh M, Yoshikawa K, Yamawaki S, Suzuki S, Hata R, Ueno S, Seki T, Kobayashi K, Toda T, Murakami K, Irie K, Klein WL, Mori H, Asada T, Takahashi R, Iwata N, Yamanaka S, Inoue H.
Cell Stem Cell. ; 12(4):487-96, 2013

■”Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells.”
Mae S, Shono A, Shiota F, Yasuno T, Kajiwara M, Gotoda-Nishimura N, Arai S, Sato-Otubo A, Toyoda T, Takahashi K, Nakayama N, Cowan CA, Aoi T, Ogawa S, McMahon AP, Yamanaka S, Osafune K.
Nat Commun. ;4:1367, 2013

■”Differentiation defective phenotypes revealed by large scale analyses of human pluripotent stem cells."
Koyanagi-Aoi M*, Ohnuki M*, Takahashi K, Okita K, Noma H, Sawamura Y, Teramoto I, Narita M, Sato Y, Ichisaka T, Amano N, Watanabe A, Morizane A, Yamada Y, Sato T, Takahashi J, Yamanaka S (*equally contributed)
Proc Natl Acad Sci U S A.;110(51):20569-74, 2013 Dec 17

■“Tsix RNA and the germline factor, PRDM14m link X-activation and stem cell reprogramming.”
Payer B, Rosenbergm M, Yamaji M, Yabuta Y, Koyanagi-Aoi M, Hayashi K, Yamanaka S, Saitou M, Lee J
Mol Cell. ; 52(6):805-18, 2013 Dec 26

2012

■”Drug screening for ALS using patient-specific induced pluripotent stem cells.”
Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, Inoue H.
Sci Transl Med. ;4(145):145ra104, 2012

■”Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells.”
Kajiwara M, Aoi T, Okita K, Takahashi R, Inoue H, Takayama N, Endo H, Eto K, Toguchida J, Uemoto S, Yamanaka S.
Proc Natl Acad Sci U S A. ;109(31):12538-43, 2012

2010

■”Induction of primordial germ cells from mouse induced pluripotent stem cells derived from adult hepatocytes.”
Imamura M, Aoi T, Tokumasu A, Mise N, Abe K, Yamanaka S, Noce T.
Mol Reprod Dev.;77(9):802-11, 2010

2009

■“Variation in the safety of induced pluripotent stem cell lines.”
Miura K, Okada Y, Aoi T, Okada A, Takahashi K, Okita K, Nakagawa M, Koyanagi M, Tanabe K, Ohnuki M, Ogawa D, Ikeda E, Okano H, Yamanaka S
Nat Biotechnol. 27(8):743-5, 2009

■”Suppression of induced pluripotent stem cell generation by p53-p21 pathway.”
Hong H, Takahashi K, Ichisaka T, Aoi T, Kanagawa O, Nakagawa M, Okita K, Yamanaka S
Nature. 460(7259):1132-5, 2009

■”Improved gene transfer into renal carcinoma cells using adenovirus vector containing RGD motif.”
Terao S, Acharya B, Suzuki T, Aoi T, Naoe M, Hamada K, Mizuguchi H, Gotoh A.
Anticancer Res. 29(8) 2997-3001, 2009

2008

■“Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts.”
*Nakagawa M*, Koyanagi M*, Tanabe K, Takahashi K, Ichisaka T, Aoi T, Okita K, Mochiduki Y, Takizawa N, Yamanaka S. (*equally contributed)
Nat Biotechnol.; 26(1):101-6, 2008 Jan

■“Generation of pluripotent stem cells from adult mouse liver and stomach cells.”
Aoi T, Yae K, Nakagawa M, Ichisaka T, Okita K, Takahashi K, Chiba T, Yamanaka S
Science. ; 321(5889), 699-702, 2008

before 2007

■“Strategies for improving outcomes for gastric cancer.”
Chiba T, Aoi T
J Gastroenterol Hepatol., 22(7): 965-7, 2007

■“Risk of subsequent development of gastric cancer in patients with previous gastric Epithelial neoplasia.”
Aoi T, Marusawa H, Sato H, Chiba T, Maruyama M
Gut, 55(4) 588-9, 2006

■“Centrosomal P4.1-associated protein Is a New Member of Transcriptional Coactivators for Nuclear Factor-kB.”
Koyanagi M, Hijikata M, Watashi K, Masui O, Shimotohno K.
J Biol Chem.; 280(13):12430-7, 2005